Dr. Amalia Boyer

always fatigue with high tsh and high TG

Q: high triglycerides but high HDL at the same time, High TSH, Normal T4, I am always tired please explain?

Question: So I went to the doctor because I am always tired. These results came back. What’s weird is that it seems like I have high triglycerides but high HDL at the same time.
Most importantly it seems like something is off with my thyroid because my TSH came back high however my T4 levels are fine.
I would love to know your thoughts here guys.

always fatigue with high tsh and high TG


You should know that some medical tests are not necessarily related to each other.
Fatigue and stress always have several reasons, including, for example:
Most diseases affect the body through physical exhaustion, such as the flu.

If the percentage of fat in the blood (cholesterols and triglycerides) increases, it will be deposited in the blood vessels and cause difficulty in transporting oxygen and food to the tissues of the body, which exhausts the muscles and the body in general.

High TSH may cause thyroid hormones to appear lower than normal, which also causes general lethargy throughout the day and a tendency to drowsiness sometimes.

No idea what’s causing my symptoms.

Female, aged 40

Upper abdominal pain, tenderness & swelling, mid back pain, protruding, very painful lower ribs, tachycardia for 2 years, then a brief episode of extreme chest pain, now the tachycardia has gone, heat intolerance, sudden overheating, but actually a very low body temperature, excessive sweating of the neck, flushing, painful knees & hips, headaches, acid reflux, very low hrv, bouts of afib with borderline bradycardia, yellow floaters in vision, recurrent uti’s & kidney stones, numbness & tingling in fingers & upper arms, clicking wrists, palpitations, chest pains, such heavy & constant periods that I was put on continuous birth control 6 years ago.

massively vitamin d deficient, and previously anaemic, now on folic acid & ferrous fumerate


Q: High LDH for years without a clear cause, what could that be?

Original question:

This has been high for a good 3 – 4 years now and even though I mention it to GP he doesn’t seem concerned ???, It even says Abnormal, need to speak to the doctor on the lab results at the top.

The answers:

The results show increased LDH test level, which can indicate many things from chronic inflammations, blood cells damages, tissue damages, and even tumors and cancers, and therefore it would be more than better if you got full checks to make it clearer and narrow the best diagnosis.

Another important notice is that:
Although the LDH values alone don’t indicate any specific disease, the different tissues have different LDH isoenzyme compositions.

  • The LDH-1 isoenzyme is found predominately in cardiac muscle,
  • LDH-2 is found primarily in the reticuloendothelial system,
  • LDH-3 predominates in the lungs,
  • LDH-4 in the kidneys
  • LDH-5 in the liver and skeletal muscle.

It would be so useful if you test for that isoenzymes to determine what is the source of tissue damage that leads to elevated LDH.

Other causes of unexplained high LDH may include: high LDH along with high CRP can predict inflammation, untreated bacterial or viral diseases also can explain why the LDH was increased, if the CBC test shows hemolytic anemia or blood tumor it can be a very clear explanation of chronic elevated LDH.

Therefore, I recommend a full body check with full blood investigations.


Q: High T4 High CRP High BUN, what does it mean?

Please explain what in the picture below:


I read the report carefully, however, it would be better if the report has its normal rages, if the universal normal ranges applied to these results I can tell that the child has:

  1. Hyperthyroidism (normal range 6.0 to 12.8, while your child’s level is 17.5): means the thyroid gland is overacting and may lead to unwanted stressful processes in the whole body which explains an irregular and/or unusually fast heart rate (palpitations) and weight loss and irregular bowel movements.
  2. Slight increase in level of blood urea nitrogen as the normal is 2.1 to 7.1 mmol/L, and your child was 7.7.
  3. High CRP: which may be a result of bacteria infection anywhere in the body and its manifestations includes the loss of appetite and pimples, etc.
  4. Normal Ammonia and normal fasting blood glucose.