MAMP letters Stand For Methamphetamine.
Methamphetamine (MAMP) is a central nervous system stimulant. It’s one of the abuse drugs called “Amphetamines “
Amphetamine belongs to the phenethylamine class. It is also the parent compound of its own structural class, the substituted amphetamines,[note 4] which includes prominent substances such as bupropion, cathinone, MDMA, and methamphetamine. As a member of the phenethylamine class, amphetamine is also chemically related to the naturally occurring trace amine neuromodulators,
The oral bioavailability of amphetamine varies with gastrointestinal pH;it is well absorbed from the gut, and bioavailability is typically over 75% for dextroamphetamine.Amphetamine is a weak base with a pKa of 9.9; consequently, when the pH is basic, more of the drug is in its lipid soluble free base form, and more is absorbed through the lipid-rich cell membranes of the gut epithelium.
Conversely, an acidic pH means the drug is predominantly in a water-soluble cationic (salt) form, and less is absorbed.Approximately 15–40% of amphetamine circulating in the bloodstream is bound to plasma proteins.Following absorption, amphetamine readily distributes into most tissues in the body, with high concentrations occurring in cerebrospinal fluid and brain tissue.
The half-life of amphetamine enantiomers differ and vary with urine pH.At normal urine pH, the half-lives of dextroamphetamine and levoamphetamine are 9–11 hours and 11–14 hours, respectively. Highly acidic urine will reduce the enantiomer half-lives to 7 hours; highly alkaline urine will increase the half-lives up to 34 hours.The immediate-release and extended release variants of salts of both isomers reach peak plasma concentrations at 3 hours and 7 hours post-dose respectively.Amphetamine is eliminated via the kidneys, with 30–40% of the drug being excreted unchanged at normal urinary pH.When the urinary pH is basic, amphetamine is in its free base form, so less is excreted.When urine pH is abnormal, the urinary recovery of amphetamine may range from a low of 1% to a high of 75%, depending mostly upon whether urine is too basic or acidic, respectively.Following oral administration, amphetamine appears in urine within 3 hours. Roughly 90% of ingested amphetamine is eliminated 3 days after the last oral dose.
Roughly 90% of ingested amphetamine is eliminated 3 days after the last oral dose.
bloody or cloudy urine
delusions of persecution, mistrust, suspiciousness, or combativeness
difficult, burning, or painful urination
false or unusual sense of well-being
feeling of unreality
frequent urge to urinate
lower back or side pain
quick to react or overreact emotionally
rapidly changing moods
sense of detachment from self or body
Seeing, hearing, or feeling things that are not there
severe mental changes
Incidence Not Known
fast, irregular, pounding, or racing heartbeat or pulse
pounding in the ears
shakiness in the legs, arms, hands, or feet
slow or fast heartbeat
talking or acting with excitement you cannot control
twitching, twisting, or uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
uncontrolled vocal outbursts or tics (uncontrolled repeated body movements)
Get emergency help immediately if any of the following symptoms of overdose occur while taking amphetamine: